| Content | Roche LightCycler 480 Instrument II Real Time PCR SystemThe system features the LightCycler 480 Instrument, a versatile, plate-based real-time PCR device that supports mono- or multicolor applications, as well as multiplex protocols. The benchtop instrument is easily customizable to meet changing user requirements, and can be integrated into everyday use as a robotically controlled, automated high-throughput solution. The LightCycler 480 Instrument is designed for general laboratory use and is not intended for use in diagnostic procedures. - Obtain fast, highly sensitive, and reproducible results for qualitative and quantitative detection of nucleic acids, mutation scanning, and SNP analysis. Use basic and advanced methods for gene expression and genotyping based on endpoint analysis or melting curves.
- Benefit from cutting-edge thermal block and optical technology that leads to excellent well-to-well homogeneity and maximized detection sensitivity.
- Use a wide range of probe formats (e.g., FRET or HybProbe probes, SimpleProbe probes, hydrolysis probes) and fluorescent dyes (e.g., SYBR Green I, ResoLight Dye, FAM, HEX, Cy5, LightCycler® Red 610, LightCycler® Red 640, and LightCycler CYAN 500).
- Choose the optimal type of multiwell plate (white or clear) to best fit your assay format, application, and workflow. Use the available adapter plate to also work with LightCycler® tube strips.
- Build a modular real-time PCR platform to meet your particular needs. Flexibly switch between plate formats and thermal block cyclers in just a few minutes with no recalibration time, and benefit from additional user-friendly software modules.
- Extract meaningful results via the state-of-the-art data analysis methods, in line with MIQE guidelines. Analyze true raw data without the need for passive reference dyes or normalization plates.
- Protect your data using a system compatible with 21 CFR part 11 requirements.
- Integrate the LightCycler® 480 System as part of a LIMS in combination with robotic pipetting and plate loading.
Use the LightCycler 480 System to perform:- Gene Quantification
- Gene detection
- Absolute quantification
- Relative quantification/gene expression analysis
- Genetic Variation Analysis
- Melt-curve genotyping with labeled probes
- Endpoint genotyping
- High-Resolution Melting (HRM)
- Multiple Plate Analysis
The LightCycler 480 Instrument shows outstanding performance in terms of:- High-performance hardware
- Innovative software
- Specially designed disposables
- Application-optimized reagents for a variety of experiments
T he Roche LightCycler 480 Instrument II Real Time PCR System is a rapid, plate-based, thermal block cycler with integrated real-time, online detection capabilities. Based on a comprehensive improvement of the Peltier-based technology incorporated in a silver block, the instrument provides extraordinary well-to-well temperature homogeneity and maximized inter-well, inter-cycle reproducibility.The special arrangement of optical components in the LightCycler480 Instrument II ensures the uniform collection of signals across the plate and makes analysis independent of the sample position on the plate.The Roche LightCycler 480 Instrument II Real Time PCR System setup enables the use of all current probe formats (e.g.,SYBR Green I, ResoLight dye for high-resolution melting, hydrolysis probes, HybProbe probes, SimpleProbe probes) and provides the ideal solution for fast and precise qualitative or quantitative detection of nucleic acids, genotyping, and mutation scanning. Channels and filters can be combined in different ways to allow flexibility in monocolor as well as multiplex assays.The LightCycler480 Software provides an intuitive, easy-to-navigate user interface for real-time PCR programming, data capture, and data analysis. It facilitates highly versatile and extensive data analysis to study gene expression and genetic variation. Specifications| Dimensions (without computer) | 60 cm x 60 cm x 54.5 cm (24 in x 24 in x 21.5 in)
(W x D x H) | | Weight | Approximately 55 kg (121 lbs) | | Computer | Windows 7 | | Sample Number | 96 or 384 | | Reaction Vessel | 96-well PCR plate, 384-well PCR plate | | Reaction Volume | 96-well PCR plate: 10 – 100 μL; 384-well PCR plate: 5 – 20 μL | | Excitation Source | Broad-spectrum, high-intensity LED (390 – 710 nm) | | Excitation Filters | 440, 465, 498, 533, 618 nm (System II) | | Detection | CCD camera | | Detection Filters | 488, 510, 580, 610,640, 660 nm (System II) | | Measuring Mode | Real-time, online (continuous display of readings) | | Temperature Control | Peltier-based heating/cooling | | Run Time | <40 minutes (384-well PCR plate) |
The Roche LightCycler 480 Instrument II Real Time PCR System consists of a variety of components that ensure maximum accuracy, versatility, and speed in quantitative real-time PCR and genotyping.LightCycler 480 Block KitsThe LightCycler 480 Block Kits consist of a block cycler unit for 96- or 384-well PCR plates, a corresponding block lid, and a storage box for both accessories. The user can quickly and easily exchange the thermal block cycler unit and the block lid. The new thermal block cycler unit and block lid are automatically detected and calibrated by the LightCycler® 480 Instrument after the instrument is turned on. No additional time-consuming calibrations are necessary.LightCycler 480 SoftwareThe LightCycler 480 Software uses unique Roche algorithms for highly accurate and robust automated data analysis. It enables users to quickly customize the system to meet different application requirements, from basic manual analysis, a wide choice of flexible quantification methods in line with MIQE guidelines, to tools for multiple plate analysis.LightCycler 480 ConsumablesThe LightCycler 480 Multiwell Plates have been adapted to the special rapid cycling environment of the LightCycler Thermal Block. LightCycler 480 Multiwell Plates are available in clear or white. White plates provide maximized sensitivity, especially with HybProbe Probe-based assays. For assays using hydrolysis probes or SYBR Green, clear plates provide an alternative for easier monitoring of PCR setup.LightCycler 480 ReagentsThe LightCycler 480 Real-Time PCR System includes generic master mixes tailor-made for each key application in genomics research (gene identification, gene quantification, variation screening, and genotyping).
Click here to compare the LightCycler 480 Kits & Reagents.Prevalidated Probes
The Universal ProbeLibrary (UPL) combines the flexibility, availability, and convenience of SYBR Green I assays with the specificity of hydrolysis probe assays. The unique combination of online assay design software and only 165 pre-tested, real-time PCR probes allows quantification of virtually any transcript in the transcriptome of a large number of organisms. | CUTERA SECRET RF 2.0CUTERA SECRET RF 2.0 MICRONEEDLING RADIO is a fractional micro-needling system (fractional radiofrequency) that exceeds the capabilities and limitations of fractional laser significantly. It is a system for extensive skin structure improvement and treatment of hyperhidrosis (radio frequency thermotherapy RFTT), based on both monopolar and fractionated on, bipolar radio frequency. An exact adjustment of the depth of the microneedles and the cold passing the epidermis allow the energy output directly into the target layer.
The needle depth is 0.5 mm to 3.5 mm can be varied, thereby opening up a wide range of treatments. The adjustable intensity of the RF energy allows for the treatment of various areas of the body with different energy performance.The ability to work specifically in the deep dermis, without damaging the epidermis, is regulated in the RF Secret by the delay time of fractional radiofrequency. The needles are inserted at a rate of milliseconds equal to a stamping process in the skin and also withdrawn immediately. Only after the needles are penetrated into the desired skin layer, is carried out for a few milliseconds, a radio frequency pulse to set heat damage. While the penetration into the skin, the needles remain always cold. In order to achieve a deep and superficial effect, the needle depths can be varied individually in the respective treatment passes.Dermal Remodeling from the Inside Out
Demand for non-surgical aesthetic procedures with little to no downtime is on the rise. More than 70% of patients are bothered by signs of aging such as fine lines and wrinkles as well as skin texture and discoloration.1Secret RF is a novel fractional radio frequency (RF) micro-needling system for tissue coagulation and hemostasis designed to stimulate and remodel collagen and address the common signs of aging. It is ideally suited for use on patients who wish to revitalize and refresh the appearance of their skin on all skin types. By adjusting the micro-needles, Secret RF can deliver energy at various depths, so that treatments can be tailored to address each patients individual concerns such as fine lines, wrinkles, acne scars, photoaging and striae at the depth required.Secret RF System
Secret RFs unique technology and customized delivery of energy enables providers to tailor treatments for a variety of skin concerns on all skin types.Customized Dermal Remodeling
Secret RF induces dermal remodeling by applying precisely controlled RF energy directly into various depths of skin from 0.5-3.5 mm – with minimally invasive micro-needles to spare the epidermis and reduce patient downtime.Skin Revitalization and Resurfacing Secret RF is a radio frequency (RF) fractional microneedling system that helps you deliver tailored energy to improve fine lines, wrinkles, and scars from the inside out. Secret RF in action
Applications include fine lines and wrinkles, photoaging, scarring, acne scars, striaeSecret RF technology Handpieces
Two sizes of treatment tips – 25 and 64 pin – give you customizable options for treating the face and body with precision and efficiency. | 2018 Vivace RF Microneedling Radio Frequency Acne ScarsTHE VIVACE EXPERIENCE
The most exciting new technology for aesthetic treatments is the combination of two methods previously used individually for skin rejuvenation, Microneedling and RF Energy. FDA-cleared for your safety, the newest generation, best-in-class Vivace RF Microneedling device, is designed for an incomparable, comfortable experience. Only Vivace boasts a precision robotic motor that brings discomfort to a virtual zero compared to any other device. The results are immediate and improve over time as well, giving you the best of both worlds. Our carefully developed recovery system ensures no one knows you just had a treatment. If you are looking for optimal results, there is no comparison to The Vivace Experience.What is Vivace Fractional RF Microneedling?
The Vivace RF Laser Radio Frequency is the newest generation of microneedling with radio frequency and is effective for fine lines and wrinkles, skin tightening, acne, acne scars, and skin tone, texture and pore size, both on and off the face. It is the most revolutionary contouring and skin tightening system for face, neck, hands and body available, producing immediate, pain-free results.Safe for all skin types, Vivace can offer similar results as ablative and fractional laser procedures, but with significantly less discomfort, downtime, and risk of complications. This revolutionary new treatment also addresses the limitations of older ‘traditional’ RF treatments and heats deeper tissues to a much higher level, which leads to greater collagen production, elastin remodeling and wound contraction previously unattainable with older technology. This is why the Vivace is a game changer in skin rejuvenation and tightening. CLICK HERE to learn moreSlate combines the best device with the newest breakthroughs in numbing, treatment serums and recovery care to create an optimal experience for you that might just keep you from needing other more invasive procedures down the road. The Vivace Experience provides the most dramatic results with less pain and less downtime. The results are both immediate and improve over time with multiple treatments. With results you can see, you’ll look and feel your best at any age.Slate Medspa is the premier Fractional RF Microneedling provider in NJ. We use the most advanced technology to provide a results-oriented skin rejuvenation program. New to Slate Medspa? Call us today at 201-477-5781 to schedule a free consultation and save 20% off your first treatment.How does Vivace Fractional RF Microneedling work?
The Vivace utilizes radio frequency and microneedling to heat the targeted area underneath the epidermis. The Vivace dramatically improves the treatment outcomes compared to other radio frequency microneedling systems.By using insulated needles, Vivace bypasses the epidermis and delivers powerful RF thermal energy to create tens of thousands of fractional coagulation zones in the dermis, facilitating a natural wound healing process. This promotes production of new collagen, remodeling of elastin and wound contraction, enhancing skin laxity. Because the thermal energy is delivered beneath the top layer of skin,Benefits of VIVACE:2018 Vivace RF Microneedling Radio Frequency Acne Scars
Minimizes/Eliminates Fine Lines and Wrinkles
Minimizes/Eliminates Acne Scars & Stretch Marks
Skin Tightening & Texture – Stimulates collagen and elastin production
Treat Sun Damage/Age Spots/Hyperpigmentation
8 Reasons why Slate LOVES Vivace™ RF Microneedling
You’ll see results quickly
Vivace works faster than any other microneedling or laser option. First, the RF Energy creates micro injuries deep in the skin in the form of a matrix. Healthy cells around the newly created matrix promote rapid healing, accelerating collagen production and skin tightening. Secondly, the invisible microchannels in the skin created by the superfine gold-tipped needles remain open for four to six hours allowing maximum absorption the key nutrients and serums applied during the treatment. This would include growth factors, HAs and other cosmeceuticals delivered to the skin in a way that no other treatment can, helping to rapidly rebuild new collagen and elastin.The average patient gets optimal results in just three treatments
Most patients experience noticeably softer, smoother and radiant skin, with improvements in tone, texture and laxity after just one treatment. We can typically achieve optimal results after only three sessions!The treatment is virtually painless
The Vivace Microneedle RF was designed for an incomparable, comfortable patient experience. The unique robotic motor is so precise, it brings the discomfort level to a virtual zero as compared to any other device. The Vivace’s ultra thin needles make it virtually pain-free. A numbing cream is applied before treatment for you to stay comfortable. Our patients here at Slate Medspa consistently report a pain level of “1” on a scale of 1 to 10.There’s no downtime
Vivace’s ultra-thin needles and robotic-assisted mechanism result in an exceptionally precise, even treatment with little-to-no bleeding. In addition, built-in LED Light therapy minimizes post-treatment redness. While we ask patients to wait until the next day before applying makeup, most feel comfortable going out without any makeup.It’s safe for almost any skin type
Patients with darker skin tones can have a more challenging time finding suitable skin resurfacing treatments, as lasers and peels that remove skin layers can risk permanent pigmentation changes. Vivace has 31 Adjustable depths, providing flexibility in treating entire depth or just down deep, bypassing damage to the top layer of skin. This means we can treat a broader array of skin types and tones with absolute precision. In addition, a variable pulse duration means the length of time the needle is engaged with tissue can be precisely controlled based on your skin profile. | Cutting Edge MLS M6 Laser Therapy Unit
The M6 therapy laser is a robotized multi-target device designed to treat patients suffering pathologies affecting a wide area, and to perform automatic applications. The distinctive feature of the M6 is the innovative multi-target functioning. Thanks to the features of the exclusive MLS multi-diodic optical group, a wide area is treated instantaneously helping to produce an immediate response of the treated tissues. The results are better and faster than with the scanning modality of traditional laser therapy products.Technical Features
Robotized optical group with 3 MLS sources – power up to 3.3 W
5 cm diameter target area highlighted by high-efficiency red light LEDs
Back-lit graphic touch-screen display
Simultaneous management of two independent channels
MLS pulse modulation frequency from 1 to 2000 Hz with 1 Hz steps
Power level 50% and 100%
Variable or fixed duty cycle
Treatment duration from 1″ to 99’59” with 1″ steps
Automatic calculation of the emitted energy according to the set parameters
Alarms and Safety Features
Laser emission warning light
Interlock (can be temporarily disabled)
Acoustic signal for the beginning and the end of the therapy, and for each treatment second (can be disabled)
Password to operate the device
Language option (Italian, English, German, Spanish)
Dimensions and Weight
27 x 17 x 62 inches; 95 lbsPower Supply
115/230V~ 50/60Hz 150VACUTTING EDGE MLS M6 Laser Therapy UnitTalk to your specialist.
Since 1983 we have been working to be the reference point in Laser Therapy and Magnetotherapy in many areas: from physiotherapy to rehabilitation, from the management of muscle and joint pain to sports medicine. The result of our work allows us today to be recognized as an international leader in the knowledge and development of advanced technologies in the field of “pain management”: a recognition confirmed in 2003 with the entry of the El.En Group. (Star segment of the Italian Stock Exchange – ELN.MI), one of the most important realities in the laser world, both for industrial and medical applications.We have always thought that research is not only confirmation, but also the necessary premise for our work. Born from the synergy between ASAlaser and the Department of Experimental and Clinical Biomedical Sciences of the University of Florence , the ASAcampus laboratory allows us to test the validity of our work and improve results over time. The result of the research is disseminated through conferences, supported thanks to important partnerships and disseminated through numerous scientific publications.Our medical devices for MLS ® Laser Therapy , Hilterapia ® and Magnetotherapy are built according to contents that we consider indispensable: advanced technologies and software, efficacy and safety, ergonomics and design. They allow for ever more targeted and personalized treatment methods. The effectiveness of our therapies is continuously tested thanks to the research carried out in ASAcampus whose results are constantly transferred to clinical applications. | Syneron Candela eTwo LaserComplete Facial Rejuvenation using the eTwoeTwo combines the unique Sublime and Sublative applications for comprehensive facial rejuvenationThe Sublime treatment combines safe and effective levels of infrared light and bipolar radiofrequency energies to remodel the dermal layer of the skin by stimulating new collagen growth.The Science of Sublime
Sublime uses the elos combination of IR and Bi-Polar RF to provide controlled deep dermal heating. This predictable heating of the deep dermis both stimulates and shortens aged collagen fibers, resulting in the immediate and long term improvement of wrinkles and facial contour.The ergonomic Sublative applicator delivers bipolar radio frequency energy via a matrix of 64 electrodes in the disposable applicator tip. The RF energy generates fractional deep dermal heating in the region of the electrode matrix to induce skin injury, thus eliciting a wound healing response. Mild to moderate wrinkles and superficial skin discoloration are reduced, and skin texture becomes more smooth and elastic.The Science of Sublative
The unique Sublative ergonomic applicator delivers bi-polar radio frequency energy via the matrix of electrodes of the disposable Sublative iD. This fractional delivery of RF energy causes micro-epidermal ablative injuries with wider spread dermal coagulation. This initiates a strong wound healing response in the dermal matrix while also minimizing the damage to the epidermis. Less affected tissue surrounding the matrix points may be stimulated by heat which helps accelerate the healing process, leading to a smoother, rejuvenated appearance of the skin.Visible Results, Low DowntimeIntelligent Feedback SystemReal time information on skin condition, impedance and the energy delivery of each pulseMinimal downtime
Safe & effective for all skin types
Quick treatments: typically 20 – 40 min
Short treatment protocol
Lightweight, compact, multi-applicator platform
Easily transports between practice locationseTwo combines the unique Sublime and Sublative applications for comprehensive facial rejuvenation in as little as one treatment.
Sublime uses the elos combination of safe and effective levels of bi-polar radio frequency energies and infrared light to remodel the deep dermal layer of the skin by stimulating new collagen growth.
Sublative fractionated bi-polar radio frequency technology places the heat energy effectively into the upper dermis where it can significantly increase both collagen and elastin with minimal epidermal disruption. | BRAND NEW BEMER CLASSIC SET COMPLETE
The BEMER Classic Set makes no compromises in terms of performance and usability. Its high quality and easy-to-connect basic equipment make the BEMER Classic Set particularly suitable for entry-level users. The control unit B.BOX Classic supports all available application modules, which can be ordered according to your individual needs. All standard treatment functions – for example, the sleep programme and three pre-set programmes for especially intensive treatments – are included with the BEMER Classic Set.Graphical, easy-to-understand displayThe BEMER Classic Set is easy to operate via the clearly structured and intuitive graphical display. The individual steps are self-evident. You can easily start all the treatment steps and programmes at the touch of a key.Three pre-set programmesIn addition to its standard treatment programmes with freely selectable intensity for the whole body, your BEMER Classic Set comes with three pre-set programmes. They facilitate intensive treatment of individual areas and can be selected via the B.BOX Classic control unit.Ten different intensity levelsChoose from up to ten individual intensity levels for treatments according to the baseline plan. They are easy to configure via the B.BOX Classic control unit.Sleep and regeneration programme BRAND NEW BEMER CLASSIC SET COMPLETEThis programme was designed specifically for overnight treatment. Recent research shows that a specific redistribution of blood takes place during sleep. This is very important for the immune system. The BEMER sleep treatment reduces not only the susceptibility to infection: nocturnal stimulation generally increases the effectiveness of treatments, enhances regeneration and deacidifies metabolism. The programme is especially helpful for the elderly and for people in the rehabilitation phase.The BEMER Pro Set is the all-inclusivepackage for your Physical Vascular Therapy. The equipment leaves nothing to be desired. The control unit B.BOX Professional in particular impresses with its exceptionally sleek design and well-conceived ergonomics. The large, clearly arranged screen display is easy to operate and also makes it possible to control up to two application devices simultaneously and independently of each other. In addition to its revolutionary control unit, the BEMER Pro Set includes a comprehensive set of application modules and accessories. The various application modules conduct the BEMER signal, generated in the control unit, directly to the areas of the body needing treatment. |
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