| Content | Rotor-Gene Q 5plex HRM
Each tube spins in a chamber of moving air, keeping all samples at precisely the same temperature during rapid thermal cycling. Detection is similarly uniform. When each tube aligns with the detection optics, the sample is illuminated and the fluorescent signal is rapidly collected from a single, short optical pathway.This thermal and optical uniformity results in sensitive, precise, and fast real-time PCR analysis (see figure “Precise real-time PCR analysis”). It also eliminates sample-to-sample variations and edge effects. These are unavoidable in traditional block-based instruments due to temperature gradients across the block and multiple, complex optical pathways. The rotary design delivers well-to-well variation ±0.02°C Uniform detection eliminating the need for ROX reference dye Fast ramping and negligible equilibration times for short run times Complete confidence in your results!The unrivaled optical range enables multiple applications Whether your essay is based on intercalating dyes such as SYBR Green, probes such as hydrolysis (TaqMan), hybridization (FRET), Scorpion probes, or other multiplex chemistries, the Rotor-Gene Q meets your requirements. With up to 6 channels spanning UV to infrared wavelengths, the cycler delivers the widest optical range currently available (see Table “Channels for optical detection”). In addition, the software allows you to create new excitation/detection wavelength combinations, which means that the Rotor-Gene Q is compatible with dyes you may use in the future.The unique centrifugal design of the Rotor-Gene Q 5plex HRM ensures optimal thermal and optical uniformity between samples, which is critical for precise and reliable analysis . Each tube spins in a chamber of moving air, keeping all samples at precisely the same temperature during rapid thermal cycling. Detection is similarly uniform. When each tube aligns with the detection optics, the sample is illuminated and the fluorescent signal is rapidly collected from a single, short optical pathway. This thermal and optical uniformity results in sensitive, precise, and fast real-time PCR analysis. The rotary design delivers up to 20 times better thermal precision in real-time cycling compared with traditional block-based instruments. Have complete confidence in your real-time PCR test by using highly precise rotary technology. Robust optical range enables multiple applications
With a choice of up to 6 excitation sources and 6 detection filters, combined with a short, fixed optical path, the
Rotor-Gene Q MDx 5plex HRM can be used for multiplex reactions (see table), ensuring minimum fluorescence variability between samples and eliminating the need for calibration and compensation. | Blue | 365 ± 20 | 460 ± 20 | Marina Blue, Edans Bothell Blue, Alexa
Fluor 350, AMCA-X, ATTO 390 | | Green | 470 ± 10 | 510 ± 5 | FAM, SYBR Green I, Fluorescein,
EvaGreen, Alexa Fluor 488 | | Yellow | 530 ± 5 | 557 ± 5 | JOE, VIC, HEX, TET, CAL Fluor
Gold 540, Yakima Yellow | | Orange | 585 ± 5 | 610 ± 5 | ROX, CAL Fluor Red 610, Cy3.5,
Texas Red, Alexa Fluor 568 | | Red | 625 ± 10 | 660 ± 10 | Cy5, Quasar 670, LightCycler
Red640, Alexa Fluor 633 | | Crimson | 680 ± 5 | 712 high pass | Quasar 705, LightCycler Red705,
Alexa Fluor 680 | | HRM | 460 ± 20 | 510 ± 5 | SYBR Green I, SYTO9, LC Green,
LC Green Plus+, EvaGreen |
Minimum maintenance; maximum convenience
The Rotor- Gene Q 5plex HRM is engineered to reduce the need for maintenance and to maximize ease of use. This saves time and costs, and keeps the instrument operational for continuous testing. The outstanding robustness of Rotor-Gene technology is proven in several thousand installations worldwide.Convenient features of the Rotor-Gene Q MDx 5plex HRM include: - Lifetime guarantee on highly stable LEDs, no expensive and time consuming lamp replacement, and no gradual performance loss
- Cost-effective and easy temperature-accuracy verification (see below)
- Optical calibration not required at installation, or when the instrument is moved
- “Plug and play” connectivity between computer and instrument
- No sample block to clean
- No condensation or bubbles in the reaction due to rotation
- Small, light, and robust instrument — simply place it where you want it
Procedure Nucleic acids are purified using the designated manual or automated purification kit that is validated for the downstream assay. After assay setup, the assays are then transferred to the Rotor-Gene Q MDx 5plex HRM for PCR and data analysis. Easy routine verification
Certified laboratories often want to verify thermal accuracy. For most cyclers, this usually requires interaction with a service engineer. With the Rotor-Gene Q MDx 5plex HRM, this is not necessary. Instead, the easy-to-use, cost-effective proprietary Rotor-Disc OTV (Optical Temperature Verification) Kit automates temperature accuracy testing. The full procedure takes less than 30 minutes and can be performed by any user.Applications The Rotor-Gene Q MDx 5plex HRM is intended for in vitro diagnostic use. The Rotor-Gene Q MDx 5plex HRM instrument is intended to be used only in combination with QIAGEN kits indicated for use with Rotor-Gene Q MDx 5plex HRM instruments for applications described in the respective QIAGEN kit handbooks. Software Software enables quantification and enhances data security
The user-friendly software provides simplicity for the routine user, as well as an open platform for the more advanced developer. Standardization in your laboratory is supported by software wizards, templates for run, processing, and analysis procedures, and various pre-defined report formats.Data security, from starting the run to exporting the results, is assured by audit trails, digital signatures, and individual user management. Each Rotor-Gene Q MDx 5plex HRM instrument is supplied with an unlimited software user license for your institute, enabling you to access and analyze your test results on as many computers as you want — in the laboratory or in the office.Features | Specifications | | Altitude | Up to 2000 m (6500 ft) | | Dimensions | Width, 37 cm (14.6 in.); Height, 27.5 cm (10.8 in.); Depth (without cables), 42 cm (16.5 in.); Depth (door open), 56 cm (22 in.) | | Heat dissipation/thermal load | Average, 0.183 kW (632 BTU/hour); Peak, 0.458 kW (1578 BTU/hour) | | Humidity | 10–75% (noncondensing) | | Operating temperature | 18–30°C (64–86°F) | | Optical System | 5 channels plus HRM; Excitation sources: high-energy light-emitting diodes; Detector: photomultiplier; Acquisition time: 4 seconds | | Overvoltage category | II | | Place of operation | For indoor use only | | Pollution level | 2 | | Power | 100–240 V AC, 50–60 Hz, <520 VA (peak); Power consumption 8 VA (standby); Mains supply voltage fluctuations are not to exceed 10% of the nominal supply voltages; F5A 250 V fuse | | Samples per run (throughput) | Tubes 0.2 ml, 36 samples/run; Strip Tubes 0.1 ml (4 tubes), 72 samples/run; Rotor-Disc 72, 72 samples/run; Rotor-Disc 100, 100 samples/run | | Software | Rotor-Gene Q software, supplied on the installation CD provided | | Storage conditions | 15–30°C (59–86°F) in manufacturer’s package; Max. 75% relative humidity (noncondensing); Environmental class 1K2 (IEC 60721-3-1) | | Technology | Real-time PCR cycler | | Thermal performance | Temperature range, 35–99°C (95–210.2°F); Temperature accuracy, ±0.5°C (calibrated using Rotor-Disc OTV procedure); Temperature resolution, ±0.02°C (smallest programmable increment); Temperature uniformity, ±0.02°C | | Transportation conditions | –25°C to 60°C (–13°F to 140°F) in manufacturer’s package; Max. 75% relative humidity (noncondensing); Environmental class 2K2 (IEC 60721-3-2) | | | | Weight | 12 kg (26.5 lb.), standard configuration |
| Syneron Candela eTwo LaserComplete Facial Rejuvenation using the eTwoeTwo combines the unique Sublime and Sublative applications for comprehensive facial rejuvenationThe Sublime treatment combines safe and effective levels of infrared light and bipolar radiofrequency energies to remodel the dermal layer of the skin by stimulating new collagen growth.The Science of Sublime
Sublime uses the elos combination of IR and Bi-Polar RF to provide controlled deep dermal heating. This predictable heating of the deep dermis both stimulates and shortens aged collagen fibers, resulting in the immediate and long term improvement of wrinkles and facial contour.The ergonomic Sublative applicator delivers bipolar radio frequency energy via a matrix of 64 electrodes in the disposable applicator tip. The RF energy generates fractional deep dermal heating in the region of the electrode matrix to induce skin injury, thus eliciting a wound healing response. Mild to moderate wrinkles and superficial skin discoloration are reduced, and skin texture becomes more smooth and elastic.The Science of Sublative
The unique Sublative ergonomic applicator delivers bi-polar radio frequency energy via the matrix of electrodes of the disposable Sublative iD. This fractional delivery of RF energy causes micro-epidermal ablative injuries with wider spread dermal coagulation. This initiates a strong wound healing response in the dermal matrix while also minimizing the damage to the epidermis. Less affected tissue surrounding the matrix points may be stimulated by heat which helps accelerate the healing process, leading to a smoother, rejuvenated appearance of the skin.Visible Results, Low DowntimeIntelligent Feedback SystemReal time information on skin condition, impedance and the energy delivery of each pulseMinimal downtime
Safe & effective for all skin types
Quick treatments: typically 20 – 40 min
Short treatment protocol
Lightweight, compact, multi-applicator platform
Easily transports between practice locationseTwo combines the unique Sublime and Sublative applications for comprehensive facial rejuvenation in as little as one treatment.
Sublime uses the elos combination of safe and effective levels of bi-polar radio frequency energies and infrared light to remodel the deep dermal layer of the skin by stimulating new collagen growth.
Sublative fractionated bi-polar radio frequency technology places the heat energy effectively into the upper dermis where it can significantly increase both collagen and elastin with minimal epidermal disruption. | CUTERA SECRET RF 2.0CUTERA SECRET RF 2.0 MICRONEEDLING RADIO is a fractional micro-needling system (fractional radiofrequency) that exceeds the capabilities and limitations of fractional laser significantly. It is a system for extensive skin structure improvement and treatment of hyperhidrosis (radio frequency thermotherapy RFTT), based on both monopolar and fractionated on, bipolar radio frequency. An exact adjustment of the depth of the microneedles and the cold passing the epidermis allow the energy output directly into the target layer.
The needle depth is 0.5 mm to 3.5 mm can be varied, thereby opening up a wide range of treatments. The adjustable intensity of the RF energy allows for the treatment of various areas of the body with different energy performance.The ability to work specifically in the deep dermis, without damaging the epidermis, is regulated in the RF Secret by the delay time of fractional radiofrequency. The needles are inserted at a rate of milliseconds equal to a stamping process in the skin and also withdrawn immediately. Only after the needles are penetrated into the desired skin layer, is carried out for a few milliseconds, a radio frequency pulse to set heat damage. While the penetration into the skin, the needles remain always cold. In order to achieve a deep and superficial effect, the needle depths can be varied individually in the respective treatment passes.Dermal Remodeling from the Inside Out
Demand for non-surgical aesthetic procedures with little to no downtime is on the rise. More than 70% of patients are bothered by signs of aging such as fine lines and wrinkles as well as skin texture and discoloration.1Secret RF is a novel fractional radio frequency (RF) micro-needling system for tissue coagulation and hemostasis designed to stimulate and remodel collagen and address the common signs of aging. It is ideally suited for use on patients who wish to revitalize and refresh the appearance of their skin on all skin types. By adjusting the micro-needles, Secret RF can deliver energy at various depths, so that treatments can be tailored to address each patients individual concerns such as fine lines, wrinkles, acne scars, photoaging and striae at the depth required.Secret RF System
Secret RFs unique technology and customized delivery of energy enables providers to tailor treatments for a variety of skin concerns on all skin types.Customized Dermal Remodeling
Secret RF induces dermal remodeling by applying precisely controlled RF energy directly into various depths of skin from 0.5-3.5 mm – with minimally invasive micro-needles to spare the epidermis and reduce patient downtime.Skin Revitalization and Resurfacing Secret RF is a radio frequency (RF) fractional microneedling system that helps you deliver tailored energy to improve fine lines, wrinkles, and scars from the inside out. Secret RF in action
Applications include fine lines and wrinkles, photoaging, scarring, acne scars, striaeSecret RF technology Handpieces
Two sizes of treatment tips – 25 and 64 pin – give you customizable options for treating the face and body with precision and efficiency.
Power:20 W ± 20%
RF frequency:2 Mh ± 20%
Intensity:0 ~ 100 Level (10 levels)
Repeat:0.2 / 0.5 / 1/2 sec / individually.
Needle Size:0.3 mm
Info about needles:25 electric needles (5 x 5, 7.8 mm x 7.8 mm / height: 1.95 mm (standard) and 16 electric needles (4 x 4, 7.8 mm x 7.8 mm / height 2.6 mm (optional)
Treatment range:1 x 1cm
Adjustable Depth:0.5 ~5 mm (0.1 steps)
Treatment duration:50 ms ~ 950 ms
Electrical power:100 ~ 240 VAC, 50/60 Hz, 220 VAMonopolar RF
Power:520 W ± 20%
RF frequency:2 Mh ± 20%
RF electrode:monopolar
Repeat:CW
RF electrode size:15APPLICATIONSFacialsNon-surgical facelift
Skin tightening
Pore reduction
Wrinkle reduction
Skin Rejuvenation (illumination)
Acne scars
Body treatmentsScar
Keratosis pilaris (Keratosis pilaris)
Stretch marks | Lutronic Clarity II
Lutronic’s Clarity II is a high-powered, dual-wavelength platform that effectively delivers a wider range of parameters to help safely and efficiently treat the broadest indications with ease. The innovative design includes: a single fiber for all spot sizes(2-25mm), intuitive interface, and no need for calibration after any parameter change. Clarity II can save time and help facilitate faster, more effective treatments.
Higher power 755/1064nm platform for effective treatments up to 45%* faster.
Brilliantly removes hair, pigment, and vascular lesions in all skin types.
IntelliTrak technology and Temperature Sensing enable increased provider confidence and treatment efficacy.Clarity II
Key Feature
1. Powerful and faster
Provide up to 25mm spot size at a useable >2 Hz
High power performance
Up to 45% faster
2. Intelligent and convenientIntelliTraking system to prevent skip area and consistent treatment
Real time skin temperature monitoring system
3. Designed for versatilityIntelligent memory function to keep track of past treatment history in detail
Zoom cartridge system for treatment areaLutronic Clarity IIHow It Works
The CLARITY II Laser System contains two separate laser resonators, Alexandrite and an Nd:YAG, which generate pulse laser energy at the nominal wavelength of 755nm and 1064nm respectively. The output of each laser generator and the 515nm aiming beam are optically combined on the laser rail so that their beam paths are identical as they exit the laser system. This allows the use of a single delivery system for either the 755nm or 1064nm wavelength.Clarity II
with IntelliTrak technologyHigher-powered 755/1064nm platform laser
Up to 2X faster Laser Hair Removal Txs*
Exclusive shorter pulsewidths available including 1ms setting
for finer facial hairs
Breakthrough intelligent capabilities
IntelliTrak technology for faster more consistent Tx coverage
Temperature Sensing for real-time skin temp feedback
during Tx
Auto-calibration in seconds saves time and
improves productivity
Advanced, easy-to-use platform
Single fiber for all 2-24mm spot cartridges
Numerous skin rejuvenation capabilities including vascular,
pigment, and toning Txs
*At settings of: 755nm, 5ms, 12J/cm2: Clarity II at 22mm, 3Hz, IntelliTrak at 18% overlap vs.
older system at 18mm, 2Hz, and est. ~18% manual overlap. Geometric treatment coverage speed is
11.4cm/second with Clarity II vs. 5.1cm/second with older system. | 2018 Lutronic Infini RF Microneedling Skin Tightening System Type: Bipolar RF (Radiofrequency) Frequency: 1 MHz Total RF Treatment Level: Up to Level 20 (Max. Power 50 W) Operation Mode:Microneedle Fractional RF (MFR) Treatment Duration:10 ms – 1,000 ms Tips: MFR Microneedle electrodes, 0.5 – 3.5 mm (Adjustable depth) SFR: Up to 144 pins Display: Color Touch LCD (Total Shot Count Displayed) Dual Switch: Foot & Finger Switch Weight: 28 kg Dimension: 362 mm (W) x 409 mm (L) x 1713 mm (H) Location: Lower Face Submental, Neck, Forehead, Periorbital Pass: Pass1: 2.25 – 3.5 mm, Pass2: 1.5 – 2.25 mm, Pass3: 1.0 – 1.25 mm Intensity: Low, Medium, High MANUFACTURER NOTES: Infini Radiofrequency Microneedling The LUTRONIC INFINI is the ideal solution to create targeted and robust coagulation zones in aging, sagging skin with pigmentation, wrinkles and laxity. Complete control over treatment depth and energy levels enables a multi-layered targeted approach for truly customized treatments, regardless of patients skin type or tanned skin. Now you can provide the best solution for results your patients demand year round. UNIQUE TECHNOLOGY, AMAZING RESULTS Infinis proven & impressive design delivers enhanced wrinkle reduction through 3-dimensional energy delivery to volumize tissue. RF energy delivered via insulated gold-coated microneedles creates precise and controllable fractionated coagulation zones within a specific layer of dermis. Adjustable depth control allows for customized and reproducible treatments of delicate areas. Infini effectively lowers the risk of PIH in dark skin types and can be safely used on patients with melasma and other types of pigmented lesions. Lutronics patented ComfortFlow technology maximizes comfort and patient satisfaction. INFINI is unique technology that puts you in control of your skin rejuvenation procedure. You control the treatment depth and energy levels to enable a multi-layered approach for customized treatments, regardless of skin type or tan. Now you can provide the best solution that will keep your patients returning and referring you to new patients.
IDEAL FOR:2018 Lutronic Infini RF Microneedling Skin Tightening– Acne Scars
– Skin tightening– Wrinkles and fine lines– Active inflammatory acne– Enlarged pores– Scar treatment– Stretch marks– Hyperhidrosis – Over production of sweat– Excessive sebum (face oil) production | 2018 Vivace RF Microneedling Radio Frequency Acne ScarsTHE VIVACE EXPERIENCE
The most exciting new technology for aesthetic treatments is the combination of two methods previously used individually for skin rejuvenation, Microneedling and RF Energy. FDA-cleared for your safety, the newest generation, best-in-class Vivace RF Microneedling device, is designed for an incomparable, comfortable experience. Only Vivace boasts a precision robotic motor that brings discomfort to a virtual zero compared to any other device. The results are immediate and improve over time as well, giving you the best of both worlds. Our carefully developed recovery system ensures no one knows you just had a treatment. If you are looking for optimal results, there is no comparison to The Vivace Experience.What is Vivace Fractional RF Microneedling?
The Vivace RF Laser Radio Frequency is the newest generation of microneedling with radio frequency and is effective for fine lines and wrinkles, skin tightening, acne, acne scars, and skin tone, texture and pore size, both on and off the face. It is the most revolutionary contouring and skin tightening system for face, neck, hands and body available, producing immediate, pain-free results.Safe for all skin types, Vivace can offer similar results as ablative and fractional laser procedures, but with significantly less discomfort, downtime, and risk of complications. This revolutionary new treatment also addresses the limitations of older ‘traditional’ RF treatments and heats deeper tissues to a much higher level, which leads to greater collagen production, elastin remodeling and wound contraction previously unattainable with older technology. This is why the Vivace is a game changer in skin rejuvenation and tightening. CLICK HERE to learn moreSlate combines the best device with the newest breakthroughs in numbing, treatment serums and recovery care to create an optimal experience for you that might just keep you from needing other more invasive procedures down the road. The Vivace Experience provides the most dramatic results with less pain and less downtime. The results are both immediate and improve over time with multiple treatments. With results you can see, you’ll look and feel your best at any age.Slate Medspa is the premier Fractional RF Microneedling provider in NJ. We use the most advanced technology to provide a results-oriented skin rejuvenation program. New to Slate Medspa? Call us today at 201-477-5781 to schedule a free consultation and save 20% off your first treatment.How does Vivace Fractional RF Microneedling work?
The Vivace utilizes radio frequency and microneedling to heat the targeted area underneath the epidermis. The Vivace dramatically improves the treatment outcomes compared to other radio frequency microneedling systems.By using insulated needles, Vivace bypasses the epidermis and delivers powerful RF thermal energy to create tens of thousands of fractional coagulation zones in the dermis, facilitating a natural wound healing process. This promotes production of new collagen, remodeling of elastin and wound contraction, enhancing skin laxity. Because the thermal energy is delivered beneath the top layer of skin,Benefits of VIVACE:2018 Vivace RF Microneedling Radio Frequency Acne Scars
Minimizes/Eliminates Fine Lines and Wrinkles
Minimizes/Eliminates Acne Scars & Stretch Marks
Skin Tightening & Texture – Stimulates collagen and elastin production
Treat Sun Damage/Age Spots/Hyperpigmentation
8 Reasons why Slate LOVES Vivace™ RF Microneedling
You’ll see results quickly
Vivace works faster than any other microneedling or laser option. First, the RF Energy creates micro injuries deep in the skin in the form of a matrix. Healthy cells around the newly created matrix promote rapid healing, accelerating collagen production and skin tightening. Secondly, the invisible microchannels in the skin created by the superfine gold-tipped needles remain open for four to six hours allowing maximum absorption the key nutrients and serums applied during the treatment. This would include growth factors, HAs and other cosmeceuticals delivered to the skin in a way that no other treatment can, helping to rapidly rebuild new collagen and elastin.The average patient gets optimal results in just three treatments
Most patients experience noticeably softer, smoother and radiant skin, with improvements in tone, texture and laxity after just one treatment. We can typically achieve optimal results after only three sessions!The treatment is virtually painless
The Vivace Microneedle RF was designed for an incomparable, comfortable patient experience. The unique robotic motor is so precise, it brings the discomfort level to a virtual zero as compared to any other device. The Vivace’s ultra thin needles make it virtually pain-free. A numbing cream is applied before treatment for you to stay comfortable. Our patients here at Slate Medspa consistently report a pain level of “1” on a scale of 1 to 10.There’s no downtime
Vivace’s ultra-thin needles and robotic-assisted mechanism result in an exceptionally precise, even treatment with little-to-no bleeding. In addition, built-in LED Light therapy minimizes post-treatment redness. While we ask patients to wait until the next day before applying makeup, most feel comfortable going out without any makeup.It’s safe for almost any skin type
Patients with darker skin tones can have a more challenging time finding suitable skin resurfacing treatments, as lasers and peels that remove skin layers can risk permanent pigmentation changes. Vivace has 31 Adjustable depths, providing flexibility in treating entire depth or just down deep, bypassing damage to the top layer of skin. This means we can treat a broader array of skin types and tones with absolute precision. In addition, a variable pulse duration means the length of time the needle is engaged with tissue can be precisely controlled based on your skin profile. |
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