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Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler

$2,800.00

THE EPPENDORF 6331 FLEXLID MASTERCYCLER NEXUS THERMAL CYCLER PROVIDES SCIENTISTS WITH FLEXIBILITY IN MANY FORMS. THE 96 WELL ALUMINIUM BLOCK CAN ACCOMODATE SEVERAL STANDARD VESSELS TYPES FROM 0.2 ML TUBES TO 96 WELL PLATES, THERE IS NO NEED TO BUY ADDITIONAL BLOCKS.

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Description

Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler

The silver block variants provide faster ramp rates than the aluminum blocks. Up to 2 eco cyclers can be connected to a programmable cycler and the configuration can also include the nexus X2 eco units, to provide a maximum of 6 independent blocks. The flexlid provides effortless height adjustment for different vessels. The Mastercycler Nexus cycler can even email you when the PCR run is complete – what else do you need from a PCR cycler?

Flexlid Concept

Due to the flexlid concept, the cycler can deal with all types of PCR consumables, from low volume all the way up to 0.5 mL PCR tubes. Of course, all common PCR plates fit – and if your throughput becomes even higher, you can just connect one or two Mastercycler nexus eco to your Mastercycler nexus

Gradient with SteadySlope technology

The Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler option of the Mastercycler pro features the SteadySlope® technology to ensure that the heating and cooling ramp rates are identical in both gradient and normal operation. Thus, you can expect identical temperature control characteristics in both optimization and routine experiments. Programming the gradient with the Control Panel and the CycleManager pro is easy and intuitive – so that novice users can get started quickly and safely.

The Eppendorf 6331 simplifies PCR temperature testing, greatly speeding up the process by performing tests across a gradient temperature. The gradient function of this thermal cycler allows for a gradient difference of 1° to 20°C across the block, so multiple samples at different temperatures can be completed in just one run. Other features include the flexlid concept, intuitive graphic programming, protocol library for ease of use, and booking schedule that acts as screensaver. The MasterCycler also offers the ability to connect up to two MasterCycler Nexus units for easy expansion.

The Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler can accommodate 96-well PCR plates, 0.2 mL PCR tubes, 0.2 mL PCR tube strips and 0.5 mL PCR tubes. This flexibility allows PCR users to select the consumables that best fit their assay. With less than 40 dB[a] noise emission, the nexus is whisper quiet, while also being energy efficient.

Manufacture Specification 

  • Capacity96 x 0.2 mL PCR tubes, 1 PCR plate (8 x 12 array), or up to 77 x 0.5 mL PCR tubes
  • Min Temperature (° F)39.2
  • Max Temperature (° F)210.2
  • Max Temperature (° C)99
  • Min Temperature (° C)4
  • Temperature Accuracy±0.2°C
  • Max Heating Rateapproximately 3°C
  • Heated Lid Temperature37 to 110°C
  • Heated Lid PressureFlexlid technology, with thermal sample protection and automatic height adjustment
  • Block DescriptionHeating technology: Peltier elements, triple circuit technology
  • Block Homogenity±0.3°C from 20 to 72°C; ±0.4°C at 95°C
  • OutputUSB, Ethernet, CAN in, CAN out

Include:

– Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler
– Certificates
– operating manuals
– wires

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SettingsEppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler removeCanon Aplio300 CV Platinum Ultrasound Machine For sale removeENDYMED PURE PLUS FOR SALE remove2018 Lutronic Infini RF Microneedling Skin Tightening removeCutting Edge MLS M6 Laser Therapy Unit For Sale removeSyneron Candela eTwo Laser For Sale remove
NameEppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler removeCanon Aplio300 CV Platinum Ultrasound Machine For sale removeENDYMED PURE PLUS FOR SALE remove2018 Lutronic Infini RF Microneedling Skin Tightening removeCutting Edge MLS M6 Laser Therapy Unit For Sale removeSyneron Candela eTwo Laser For Sale remove
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Description

THE EPPENDORF 6331 FLEXLID MASTERCYCLER NEXUS THERMAL CYCLER PROVIDES SCIENTISTS WITH FLEXIBILITY IN MANY FORMS. THE 96 WELL ALUMINIUM BLOCK CAN ACCOMODATE SEVERAL STANDARD VESSELS TYPES FROM 0.2 ML TUBES TO 96 WELL PLATES, THERE IS NO NEED TO BUY ADDITIONAL BLOCKS.

The Canon Aplio 300 Platinum lowers the price by removing its standard option, but still uses the same system architecture like the Aplio 500 Platinum and the Aplio 400 Platinum, which a user can enjoy a great fundamental image quality of those two higher grade systems. The Canon Aplio 300 is positioned as a high-end grade system, and holds a very good reputation in Radiology with a wide selection of intraoperative transducers, superb fundamental image quality, and outstanding and dedicated premium radiology options such as Smart Fusion, Shear Wave, and Contrast Harmonic Imaging (CHI)The PURE+ is offered in two configurations:FSR + TC: Fixed FSR handpiece + one exchangeable connector suitable for all TC handpieces: iFine, Small and Large TC Complete: Two exchangeable connectors on each side, suitable for all TC handpieces: iFine, Shaper, Small and LargeThe iFine treatment Handpiece – specially engineered to target fine lines and wrinkles found in the delicate thin – skin areas around the eyes, providing: Smoother, tighter skin around the eyes. Reduced under eye sagging and improved eye contour. Reduced hooding to reveal more of the eyelid. More youthful, less tired looking eyes. Softening of fine line enabling easier application of make-up.

2018 Lutronic Infini RF Microneedling Skin Tightening Laser with RF Microneedling Handpiece - with CONSUMABLE SUPPORT - Free Shipping -

The M6 therapy laser is a robotized multi-target device designed to treat patients suffering pathologies affecting a wide area, and to perform automatic applications. The distinctive feature of the M6 is the innovative multi-target functioning. Thanks to the features of the exclusive MLS multi-diodic optical group, a wide area is treated instantaneously helping to produce an immediate response of the treated tissues. The results are better and faster than with the scanning modality of traditional laser therapy products.eTwo combines the unique Sublime and Sublative applications for comprehensive facial rejuvenation in as little as one treatment. Sublime uses the elos combination of safe and effective levels of bi-polar radio frequency energies and infrared light to remodel the deep dermal layer of the skin by stimulating new collagen growth. Sublative fractionated bi-polar radio frequency technology places the heat energy effectively into the upper dermis where it can significantly increase both collagen and elastin with minimal epidermal disruption.
Content

Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler

The silver block variants provide faster ramp rates than the aluminum blocks. Up to 2 eco cyclers can be connected to a programmable cycler and the configuration can also include the nexus X2 eco units, to provide a maximum of 6 independent blocks. The flexlid provides effortless height adjustment for different vessels. The Mastercycler Nexus cycler can even email you when the PCR run is complete – what else do you need from a PCR cycler?Flexlid ConceptDue to the flexlid concept, the cycler can deal with all types of PCR consumables, from low volume all the way up to 0.5 mL PCR tubes. Of course, all common PCR plates fit – and if your throughput becomes even higher, you can just connect one or two Mastercycler nexus eco to your Mastercycler nexusGradient with SteadySlope technologyThe Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler option of the Mastercycler pro features the SteadySlope® technology to ensure that the heating and cooling ramp rates are identical in both gradient and normal operation. Thus, you can expect identical temperature control characteristics in both optimization and routine experiments. Programming the gradient with the Control Panel and the CycleManager pro is easy and intuitive – so that novice users can get started quickly and safely.The Eppendorf 6331 simplifies PCR temperature testing, greatly speeding up the process by performing tests across a gradient temperature. The gradient function of this thermal cycler allows for a gradient difference of 1° to 20°C across the block, so multiple samples at different temperatures can be completed in just one run. Other features include the flexlid concept, intuitive graphic programming, protocol library for ease of use, and booking schedule that acts as screensaver. The MasterCycler also offers the ability to connect up to two MasterCycler Nexus units for easy expansion.The Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler can accommodate 96-well PCR plates, 0.2 mL PCR tubes, 0.2 mL PCR tube strips and 0.5 mL PCR tubes. This flexibility allows PCR users to select the consumables that best fit their assay. With less than 40 dB[a] noise emission, the nexus is whisper quiet, while also being energy efficient.Manufacture Specification 
  • Capacity96 x 0.2 mL PCR tubes, 1 PCR plate (8 x 12 array), or up to 77 x 0.5 mL PCR tubes
  • Min Temperature (° F)39.2
  • Max Temperature (° F)210.2
  • Max Temperature (° C)99
  • Min Temperature (° C)4
  • Temperature Accuracy±0.2°C
  • Max Heating Rateapproximately 3°C
  • Heated Lid Temperature37 to 110°C
  • Heated Lid PressureFlexlid technology, with thermal sample protection and automatic height adjustment
  • Block DescriptionHeating technology: Peltier elements, triple circuit technology
  • Block Homogenity±0.3°C from 20 to 72°C; ±0.4°C at 95°C
  • OutputUSB, Ethernet, CAN in, CAN out
Include:– Eppendorf 6331 Flexlid Mastercycler Nexus Thermal Cycler – Certificates – operating manuals – wires
Canon Aplio300 CV Platinum Ultrasound Machine
The Canon Aplio Platinum series share the system architecture; therefore, functions in a manner similar to and are intended for the same use. The systems are overall heavier and larger than newer GE and Philips products; however, the Canon Aplio Platinum series became stable and reliable due to the last 4 to 5 consecutive upgrades since its initial launch in 2012.The Canon Aplio 300 Platinum lowers the price by removing its standard option, but still uses the same system architecture like the Aplio 500 Platinum and the Aplio 400 Platinum, which a user can enjoy a great fundamental image quality of those two higher grade systems. The Canon Aplio 300 is positioned as a high-end grade system, and holds a very good reputation in Radiology with a wide selection of intraoperative transducers, superb fundamental image quality, and outstanding and dedicated premium radiology options such as Smart Fusion, Shear Wave, and Contrast Harmonic Imaging (CHI).The Canon Aplio Platinum series provide a number of clinical tools that provide wider clinical utilities and save scanning time by providing better visualization in a short time. The Superb Micro Vascular Imaging (SMI) is one that increases physician’s clinical productivity and diagnostic efficiency with better visualization of low-velocity blood flow. The MicroPure function is the function that increases comfort and confidence of diagnosis by better visualizing small structures such as a small calcification in breast. The Canon Aplio Platinum series support unique linear (PLT-308P) and convex (PVT-350BTP) transducers that much improve the needle biopsy procedure by offering the method that a needle can be inserted and visualized in the middle of transducer, not from the edge of a transducer.The Canon products in general look like a technology oriented product, rather than a clinical oriented product. With this series, Canon has achieved fully digital beamforming technology, which is fully integrated into the Aplio Platinum series. The weight of each Platinum series is still high, above 320 lbs. The monitor size is 17-inches, but upgradable to 19-inches. Although the Canon Aplio Platinum holds good quality and reputation in Radiology, they still need to be improved in cardiology and OB/GYN’s workflow, automation, and 4D quality, comparing GE or Samsung products to satisfy customers.
CANON APLIO 300 CV PLATINUM ULTRASOUND MACHINE
Probes
Canon Aplio 300 Platinum Probes/Transducers:Convex Probe PVT-375BT(6C1) PVT-375SC(6Cs1) PVT-674BT(9C3)Micro Convex Probe PVT-382BT(6MC1) PVT-712BT(11MC4)Endo Cavity Probe PVT-661VT(9C3) PVT-674BT(10C3) PVT-781VT(11C3) PVT-781VTE(11C3)3/4D Convex Probe PVT-375MV(6CV1) PVT-382MV(6MCV1) PVT-675MV(8CV2) PVT-675MVL(9CV2) PVT-681MV(9CV3) PVT-681MVL(11CV3) PLT1204MV(12LV7)Intra Operative Probe PVT-350BTP(6CP1) PVT-745BTF(11CI4) PVT-745BTH(11CI4) PVT-745BTV(11CI4) PLT-705BTF(11LI4) PLT-705BTH(11LI4)Hockey Stick Probe PLT1202S(14L7)BI Plane Probe PVL-715RST(11CL4)Linear Array Probe PlT-308P(6LP3) PLT-604AT(10L4) PLT-704AT(11L5) PLT-704SBT(11L4) PLT-705BT(11L3) PLT-805AT(12L5) PLT-1005BT(14L5) PLT-1204BT(18L7) PLT-1204BX(18LX7)Sector Probe PST-25BT(5S1) PST-30BT(5S2) PST-50BT(6S3) PST-65AT(9S4)TEE PET-508MA(7S3) PET510MA(7S3) PET-510MB(7S3) PET-511BTM(8SM2) PET-512MA(8S2) PET-512MC(8SM2) PET-512MD(8SM2)Laparoscopic Probe PET-805LA(12LI4)Pencil Probe PC-20M(P2) PC-50M(P5)
Features
Features:• 19-inch LCD monitor • DVD/CD drive • ApliPure+(Spatial Compounding) • Quick Scan • TDI • QSP • HPRF • DICOM Media Storage
Options
Options:• CW Kit • ECG, PCG, and Pulse sensor • Mounting Kit for Peripheral Unit • Footswitch • Gel Warmer • M-TEE Hanger Kit • 4D Unit • Battery Kit • Transducer Holder(Right) Kit • Transducer Holder(Left) Kit • Transducer Cable Hanger Kit • CV Kit • Wireless LAN Kit • DICOM Kit • Stress Echo Kit • 2D Wall Motion Tracking Kit • CHI Kit • ApliPureTM Plus Kit • Differential THI Kit • Precision Imaging Kit • Tissue specific Optimization Kit • 4D STIC Imaging Kit • Luminace Kit • Smart 3D Kit • Protocol Assistant Kit • Superb Micro Vascular Imaging Kit • Trapezoid Scan Kit • Dynamic FlowTM Kit • MicroPureTM Kit • Ealstography-FLR Kit • Elastogrpahy Kit • FLR Kit • Shear wave Kit • Panoramic View Kit • Vascular Index Kit • FLEX-M Kit • Auto NT Kit • Probe 4 Port Kit • Security Management Kit • Local Language Key-Top Kit
Applications : Canon Aplio300 CV Platinum Ultrasound Machine• Abdomen • Women’s Helacre Care(GYN & Breast) • Obstetrics • Fetal Echo • Vascular • Transcranial • Small Parts(Breast, Thyroid, Testis…) • MSK/Anesthesiology • Pediatrics • Urology (Renal, Prostate…) • Adult Echocardiography • Pediatric Echocardiography • Neonate Echocardiography • Stress Echocardiography • Adult Transesophageal Echocardiography • Pediatric Transesophageal Echocardiography • Internal Medicine w/ Shared Service • Surgery • Interventional Radiology • Contrast Imaging_General Imaging • Contrast Imaging_Cardiac • Bowel Imaging • Strain Elastography
ENDYMED PURE PLUS Input Power:100-120V, 50-60Hz, 2A or 220-240V, 50-60Hz, 1A Power Consumption:220 W Fuses:2 x 1.6A for 220V; 2 x 3.15A for 110V Output Power:Up to 50 Watts Output Frequency:1MHz Working Temperature:+10°C – +25°C Dimensions:(H x W x D) 600 x 305 x 365 mm Weight:10 kg GOOD THINGS COMES IN SMALL PACKAGES – THE PURE+ The Pure+ by Endymed Pure Plus, powered by our FDA cleared, patented 3DEEPRF technology. The PURE+ offers professional grade Fractional Skin Resurfacing and superior body, facial and neck tightening and contouring treatments, all on one easy to use, compact platform.The PURE+ offers complete flexibility with exchangeable treatment handpieces – one PURE+ console can be configured any way you like to provide you and your clients with the most effective and popular treatments available today.The PURE+ is offered in two configurations:FSR + TC: Fixed FSR handpiece + one exchangeable connector suitable for all TC handpieces: iFine, Small and Large TC Complete: Two exchangeable connectors on each side, suitable for all TC handpieces: iFine, Shaper, Small and LargeThe iFine treatment Handpiece – specially engineered to target fine lines and wrinkles found in the delicate thin – skin areas around the eyes, providing: Smoother, tighter skin around the eyes. Reduced under eye sagging and improved eye contour. Reduced hooding to reveal more of the eyelid. More youthful, less tired looking eyes. Softening of fine line enabling easier application of make-up.3Deep Small-Medium Handpiece Designed to treat wrinkles and lax skin on the face, neck and upper body.3Deep Fractional Skin Resurfacing Handpiece Specially designed for fractional skin resurfacing and treatment of skin roughness, hyperpigmentation, and wrinkles and scars on both facial and body. The FSR handpiece contains a matrix of 112 tiny electrodes, allowing for the first time simultaneous fractional micro-ablation of the epidermis, together with volumetric heating of 100% of the dermis. This technology provides the capability to differentiate between micro-ablation and dermal heating which appears to be the optimal multi-layer treatment to affect aging skin and atrophic acne scars.3Deep Shaper Handpiece Major innovation in RF skin tightening, body shaping and contouring, and cellulite treatment for large body areas. The handpiece’s unique engineered electrode surface is 40.7 cm2 allowing for shorter treatment times (20 minute abdomen treatment, 30 minute cellulite treatments for the thighs and buttocks). Deeper, controlled energy penetration tightens and firms the skin by stimulating the body’s natural collagen renewal process, providing better and more effective results.
2018 Lutronic Infini RF Microneedling Skin Tightening

System Type: Bipolar RF (Radiofrequency)

Frequency: 1 MHz

Total RF Treatment Level: Up to Level 20 (Max. Power 50 W)

Operation Mode:Microneedle Fractional RF (MFR)

Treatment Duration:10 ms – 1,000 ms

Tips: MFR Microneedle electrodes, 0.5 – 3.5 mm (Adjustable depth) SFR: Up to 144 pins

Display: Color Touch LCD (Total Shot Count Displayed)

Dual Switch: Foot & Finger Switch

Weight: 28 kg

Dimension: 362 mm (W) x 409 mm (L) x 1713 mm (H)

Location: Lower Face Submental, Neck, Forehead, Periorbital

Pass: Pass1: 2.25 – 3.5 mm, Pass2: 1.5 – 2.25 mm, Pass3: 1.0 – 1.25 mm

Intensity: Low, Medium, High

MANUFACTURER NOTES:

Infini Radiofrequency Microneedling

The LUTRONIC INFINI is the ideal solution to create targeted and robust coagulation zones in aging, sagging skin with pigmentation, wrinkles and laxity. Complete control over treatment depth and energy levels enables a multi-layered targeted approach for truly customized treatments, regardless of patients skin type or tanned skin. Now you can provide the best solution for results your patients demand year round.

UNIQUE TECHNOLOGY, AMAZING RESULTS

Infinis proven & impressive design delivers enhanced wrinkle reduction through 3-dimensional energy delivery to volumize tissue. RF energy delivered via insulated gold-coated microneedles creates precise and controllable fractionated coagulation zones within a specific layer of dermis. Adjustable depth control allows for customized and reproducible treatments of delicate areas. Infini effectively lowers the risk of PIH in dark skin types and can be safely used on patients with melasma and other types of pigmented lesions. Lutronics patented ComfortFlow technology maximizes comfort and patient satisfaction.

INFINI is unique technology that puts you in control of your skin rejuvenation procedure. You control the treatment depth and energy levels to enable a multi-layered approach for customized treatments, regardless of skin type or tan. Now you can provide the best solution that will keep your patients returning and referring you to new patients.

IDEAL FOR:2018 Lutronic Infini RF Microneedling Skin Tightening

– Acne Scars

– Skin tightening– Wrinkles and fine lines– Active inflammatory acne– Enlarged pores– Scar treatment– Stretch marks– Hyperhidrosis – Over production of sweat– Excessive sebum (face oil) production

Cutting Edge MLS M6 Laser Therapy Unit

The M6 therapy laser is a robotized multi-target device designed to treat patients suffering pathologies affecting a wide area, and to perform automatic applications. The distinctive feature of the M6 is the innovative multi-target functioning. Thanks to the features of the exclusive MLS multi-diodic optical group, a wide area is treated instantaneously helping to produce an immediate response of the treated tissues. The results are better and faster than with the scanning modality of traditional laser therapy products.Technical Features Robotized optical group with 3 MLS sources – power up to 3.3 W 5 cm diameter target area highlighted by high-efficiency red light LEDs Back-lit graphic touch-screen display Simultaneous management of two independent channels MLS pulse modulation frequency from 1 to 2000 Hz with 1 Hz steps Power level 50% and 100% Variable or fixed duty cycle Treatment duration from 1″ to 99’59” with 1″ steps Automatic calculation of the emitted energy according to the set parameters Alarms and Safety Features Laser emission warning light Interlock (can be temporarily disabled) Acoustic signal for the beginning and the end of the therapy, and for each treatment second (can be disabled) Password to operate the device Language option (Italian, English, German, Spanish) Dimensions and Weight 27 x 17 x 62 inches; 95 lbsPower Supply 115/230V~ 50/60Hz 150VACUTTING EDGE MLS M6 Laser Therapy UnitTalk to your specialist. Since 1983 we have been working to be the reference point in Laser Therapy and Magnetotherapy in many areas: from physiotherapy to rehabilitation, from the management of muscle and joint pain to sports medicine. The result of our work allows us today to be recognized as an international leader in the knowledge and development of advanced technologies in the field of “pain management”: a recognition confirmed in 2003 with the entry of the El.En Group. (Star segment of the Italian Stock Exchange – ELN.MI), one of the most important realities in the laser world, both for industrial and medical applications.We have always thought that research is not only confirmation, but also the necessary premise for our work. Born from the synergy between ASAlaser and the Department of Experimental and Clinical Biomedical Sciences of the University of Florence , the ASAcampus laboratory allows us to test the validity of our work and improve results over time. The result of the research is disseminated through conferences, supported thanks to important partnerships and disseminated through numerous scientific publications.Our medical devices for MLS ® Laser Therapy , Hilterapia ® and Magnetotherapy are built according to contents that we consider indispensable: advanced technologies and software, efficacy and safety, ergonomics and design. They allow for ever more targeted and personalized treatment methods. The effectiveness of our therapies is continuously tested thanks to the research carried out in ASAcampus whose results are constantly transferred to clinical applications.
Syneron Candela eTwo LaserComplete Facial Rejuvenation using the eTwoeTwo combines the unique Sublime and Sublative applications for comprehensive facial rejuvenationThe Sublime™ treatment combines safe and effective levels of infrared light and bipolar radiofrequency energies to remodel the dermal layer of the skin by stimulating new collagen growth.The Science of Sublime Sublime uses the elos combination of IR and Bi-Polar RF to provide controlled deep dermal heating. This predictable heating of the deep dermis both stimulates and shortens aged collagen fibers, resulting in the immediate and long term improvement of wrinkles and facial contour.The ergonomic Sublative™ applicator delivers bipolar radio frequency energy via a matrix of 64 electrodes in the disposable applicator tip. The RF energy generates fractional deep dermal heating in the region of the electrode matrix to induce skin injury, thus eliciting a wound healing response. Mild to moderate wrinkles and superficial skin discoloration are reduced, and skin texture becomes more smooth and elastic.The Science of Sublative The unique Sublative ergonomic applicator delivers bi-polar radio frequency energy via the matrix of electrodes of the disposable Sublative iD. This fractional delivery of RF energy causes micro-epidermal ablative injuries with wider spread dermal coagulation. This initiates a strong wound healing response in the dermal matrix while also minimizing the damage to the epidermis. Less affected tissue surrounding the matrix points may be stimulated by heat which helps accelerate the healing process, leading to a smoother, rejuvenated appearance of the skin.Visible Results, Low DowntimeIntelligent Feedback SystemReal time information on skin condition, impedance and the energy delivery of each pulseMinimal downtime Safe & effective for all skin types Quick treatments: typically 20 – 40 min Short treatment protocol Lightweight, compact, multi-applicator platform Easily transports between practice locationseTwo combines the unique Sublime and Sublative applications for comprehensive facial rejuvenation in as little as one treatment. Sublime uses the elos combination of safe and effective levels of bi-polar radio frequency energies and infrared light to remodel the deep dermal layer of the skin by stimulating new collagen growth. Sublative fractionated bi-polar radio frequency technology places the heat energy effectively into the upper dermis where it can significantly increase both collagen and elastin with minimal epidermal disruption. 
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